TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds

MedicalXpress | mars 31, 2026

A study by researchers at the University of California San Diego could make it easier to treat breast cancer by uncovering a new way the body helps prevent its spread. The scientists discovered a new role for an inflammatory protein called TYK2 in mechanotransduction, the process by which cells sense and respond to their physical environment. Understanding mechanotransduction can provide insights into how cancer spreads and provide new avenues for treatment.