How calcium channel mutations disrupt early brain development in childhood epilepsy

MedicalXpress | Apr 03, 2026

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium channel mutations disrupt early brain development and predispose children to epilepsy and related cognitive challenges. The findings, published in Neuron, shed new light on how subtle genetic changes can alter brain circuits long before seizures begin.