Antidepressant unable to prevent chemotherapy-associated nerve damage

MedicalXpress | avr. 11, 2026

A randomized trial conducted by the Alliance for Clinical Trials in Oncology has found that duloxetine, a medication commonly used to treat chronic pain and psychiatric conditions, does not prevent nerve damage caused by chemotherapy in patients with colorectal cancer. The primary analysis of Alliance A221805 was published in JCO Oncology Advances