Gut microbes reveal a surprising tie to cortisol spikes during acute stress

MedicalXpress | 四月 16, 2026

The gut microbiome influences numerous physiological processes. Researchers at the University of Vienna have now demonstrated for the first time that, in healthy adults, the diversity of gut bacteria and their capacity to produce certain metabolites are associated with the acute stress response—particularly stress reactivity. Higher microbial diversity was associated with stronger hormonal and subjectively perceived stress reactivity. The results suggest that the gut microbiome may play a role in regulating the acute stress response. The study was published in Neurobiology of Stress.