Genetic study reveals likely cause of common heart valve defect

MedicalXpress | 四月 24, 2026

New clues from genetic research may help explain what causes the most common heart defect present at birth. Researchers at KTH Royal Institute of Technology and Karolinska Institutet have identified rare DNA changes during fetal development that can lead to the aortic valve forming with only two cusps instead of three, a condition known as bicuspid aortic valve (BAV).