How changes to proteins can alter drug interactions for new precision therapies

MedicalXpress | 五月 06, 2026

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they're produced. Known as post-translational modifications, or PTMs, these can change how a protein folds, where it travels and how it behaves. Now, scientists at Scripps Research have shown that PTMs also play a major role in determining whether proteins can bind to drug-like molecules.