Common NSAIDs in first trimester show no birth defect link, data suggest

MedicalXpress | мая 14, 2026

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, taken during the first trimester of pregnancy are not associated with an increased risk of major birth defects, according to a new study published in PLOS Medicine by Sharon Daniel of Ben-Gurion University of the Negev and Clalit Health Services, Beer-Sheva, Israel, and colleagues.