Why does ALS pathology spread differently among patients?

MedicalXpress | mai 20, 2026

A research team at the Brain Research Institute, Niigata University has found that APOE ε4, a genetic factor best known for increasing the risk of Alzheimer's disease, may also influence how pathological changes spread in amyotrophic lateral sclerosis (ALS). The findings were published in Acta Neuropathologica.