Scientists identify metabolic target to overcome chemotherapy resistance in ovarian cancer

MedicalXpress | mai 28, 2026

Many cancers can be treated by administering DNA-damaging agents, such as platinum-based chemotherapy, because the resulting DNA damage causes the cancer cells to die. A subset of cancers, however, including ovarian cancers, can repair their own DNA. Because such cancers survive despite chemotherapy, ovarian cancer patients whose tumors are DNA repair proficient have historically faced a poor prognosis and commonly recur within six months.