Mirror-image pain after stroke may arise as LPA-driven inflammation crosses corpus callosum

MedicalXpress | 六月 03, 2026

A stroke is a devastating condition that disrupts proper brain function. After a stroke, many patients will typically experience pain in the limbs on the side of their bodies opposite to the brain lesion. In rare cases, pain also develops on the same side as the lesion, spreading bilaterally in a mirror-like manner. This is a phenomenon known as bilateral pain, or mirror-image pain.