Potential gene therapy for late-stage Parkinson's side-effects uncovered

MedicalXpress | Jun 03, 2026

Northwestern Medicine scientists have discovered that suppressing excitatory synaptic transmission in a small group of neurons in the brain may reverse levodopa-induced dyskinesia in patients with late-stage Parkinson's disease without reducing the symptomatic benefits of levodopa treatment, according to a recent study published in Neuron.