Gene mutations may explain some spontaneous spinal fluid leaks

MedicalXpress | 六月 17, 2026

Researchers at Cedars-Sinai Health Sciences University and Johns Hopkins University have identified genetic mutations that may explain why some people develop a spontaneous cerebrospinal fluid (CSF) leak in the spine. The findings, published in The Lancet Neurology, may lead to earlier diagnosis and more targeted treatments for the painful and often disabling condition.