Large MRI analysis uncovers brain-region thinning tied to depression

MedicalXpress | juin 27, 2026

Major depressive disorder (MDD) is a psychiatric condition characterized by persistent feelings of sadness, a loss of interest in everyday activities, altered sleeping and/or eating patterns, low energy, and difficulty concentrating on tasks. While it is one of the most widespread mental health disorders worldwide, its unique neural and brain-related signatures have not yet been fully uncovered.