Cognitive flexibility problems may arise months before memory impairment in Alzheimer's

MedicalXpress | juil. 01, 2026

When most people think about Alzheimer's disease, memory loss is usually the first thing that comes to mind. Forgetting a loved one's name, missing appointments or repeatedly misplacing everyday items are often considered early warning signs. But what if the disease begins affecting the brain long before memory problems become noticeable? New research from scientists at Texas A&M Health suggests that another change in brain function may appear even earlier: difficulty adapting when circumstances change.