Fibronectin pathway may drive Marfan aortic damage, opening new drug targets

MedicalXpress | juil. 06, 2026

A new study published in Nature Communications identifies a molecular signaling pathway that contributes to the development of life-threatening aortic aneurysms and dissections in Marfan syndrome, a genetic disorder affecting connective tissue. The findings provide new insight into how structural alterations in the aortic wall lead to disease progression and point to potential therapeutic targets.