Unmedicated women with depression do not tolerate heat as well as those on SSRIs

MedicalXpress | Jul 09, 2026

Media stories, social media posts and the U.S. Centers for Disease Control and Prevention have asserted that selective serotonin reuptake inhibitors (SSRIs)—a class of medication commonly used to treat mental health conditions including depression and anxiety—may increase people's vulnerability to heat, leading to concerns that people who take SSRIs are at increased risk of heat-related illnesses in hot weather.