Deleting two molecular gatekeepers sharply reduces metastasis in mouse tumors

MedicalXpress | juil. 16, 2026

By analyzing individual cancer cells, researchers from the Université Libre de Bruxelles (ULB) discovered the transcriptional regulators governing epithelial-to-mesenchymal transition (EMT) in tumors and identified key master regulators that control metastasis, revealing potential therapeutic vulnerabilities to block metastatic dissemination.